Met-Rx CLA with Raspberry Ketones Reviews
Met-Rx CLA with Raspberry Ketones Myolepetin 1000 is designed specifically to “support your body shaping and toning goals.”
According to advertisements, Met-RX is infused with bioactivie ingredients that boost energy and increase oxidative enzyme activity.
Although this product is still very new, dieters are discussing its toning potential in bodybuilding forums and weight loss sites.
To find out if CLA with Raspberry Ketones could really live up to the hype, I investigated the ingredients and its weight loss potential.
Surprisingly enough, Met-Rx’s new formula only contains 2 ingredients:
CLA (from Safflower Oil). Short for conjugated linoleic acid, this fatty acid might reduce body fat deposits and improve immune function. According to WebMD experts, CLA might reduce the risk of certain kinds of cancers as well. 
Raspberry Ketone. This aromatic compound is purported to increase lean body mass and promote weight loss. Supposedly it achieves this effect by regulating adiponectin levels, a hormone that manages weight, blood sugar, and cholesterol levels.
Is There Clinical Research?
While it’s nice to see an uncluttered formula, it also seems risky for diet pill manufacturers to rely on just 2 ingredients for weight loss. Not all consumers respond well to specific ingredients, and including additional fat burners or appetite suppressants may provide results when other ingredients fail.
Consequently, these two ingredients have to count if they’re going to help you lose weight.
First, let’s take a look at conjugated linoleic acid.
In animal studies, moderate CLA doses reduced fat gain while maintaining insulin levels. After 30 days of use, subjects who received CLA experienced “modest reduction of fat gain, ameliorates macrophage infiltration into adipose tissue and expression of pro-inflammatory cytokines.”
What does this mean to you? It means this fatty acid has the potential to fight fat.
But before we jump on the CLA bandwagon, we still need to find out if it works in human subjects.
In 2001, scientists observed the efficacy and tolerability of CLA in healthy exercising humans. Participants were given either a placebo or .6 gram dosage 3 times daily. After 12 weeks, those who were given CLA lost significant body fat compared to their placebo counterparts with no negative side effects. 
However, dieters should note that the reduction was in body fat, not body weight. Furthermore, the study featured 1.8 grams CLA daily, whereas CLA with Raspberry Ketones contains 1 gram taken 3 times daily.
According to WebMD, taking larger doses CLA “do not seem to offer any additional benefit,” and may, in fact, increase side effect risk. These side effects include stomach upset, diarrhea, nausea, and fatigue.
And what about raspberry ketone?
Despite Dr. Oz dubbing raspberry ketone as a “fat burner in a bottle,” his recommendation may have been premature.
Clinical studies linking raspberry ketone are currently limited to animal studies, not to humans.
In 2005, Japanese researchers found raspberry ketone was structurally similar to capsaicin and synephrine, both widely known for their thermogenic abilities.
Subjects who were given RK (raspberry ketone) experienced “significantly increased norepinephrine-induced lipolysis.” Researchers subsequently concluded, “RK prevents and improves obesity and fatty liver.” 
Though these results were promising, further evidence is needed to know if raspberry ketone has the same effect on human subjects and if it’s safe to use regularly.
Does Dr. Oz Recommend It?
Dr. Oz has recommended both CLA and raspberry ketone for weight loss in his career. Nevertheless, he has never recommended a CLA and raspberry ketone product, let alone Met-Rx CLA with Raspberry Ketone.
In fact, he does not endorse any specific supplement or product. According to his recent statement, “I am not and have never been a paid spokesperson for any particular brand, supplement, or product. . .” 
Is Met-Rx CLA with Raspberry Ketone Safe?
As mentioned above, CLA is known to cause negative side effects such as nausea, diarrhea, stomach upset, and fatigue. So, approach this supplement with caution.
Raspberry ketone, on the other hand, has not been studied for safety or efficacy. It is unknown whether raspberry ketone is safe to use on a short-term basis, let alone regularly.
According to WebMD experts, “there are some concerns about the safety of raspberry ketone because it is chemically related to a stimulant called synephrine. Therefore, it is possible that raspberry ketone might cause feelings of jitteriness, increase blood pressure, or rapid heart beat.” 
Consequently, it’s best to start off with a small dosage then work your way up to the full amount depending on your tolerance.
Is It Easy to Use?
Met-Rx CLA with Raspberry Ketone’s greatest feature is convenience. There are no strict schedules and no dieting restrictions. Simply take 1 softgel three times daily, preferably with meals.
For best results, use in conjunction with a reduced calorie diet and daily exercise program.
If you are taking medication or have a medical condition, it is imperative that you consult your doctor prior to using CLA with Raspberry Ketone or making any significant changes to your current lifestyle.
Where to Buy CLA with Raspberry Ketones
CLA with Raspberry Ketone is difficult to find and purchase online. As far as I can tell, this supplement is only available at Bodybuilding.com for $19.83 a bottle and Netrition.com for $18.99 a bottle.
I assume as the product gains popularity that additional distributors will be available, so keep an eye out for this product.
More About Met-Rx
Met-Rx is an American brand of nutritional supplements that has been sold several times in the last few years. The company was originally founded by Dr. Scott Connelly, and its first product was intended to prevent critically ill patients from losing muscle mass.
Currently, Met-Rx is owned by NBTY, or Nature’s Bounty Inc.
In the past, Met-RX failed to provide peer-reviewed documentation to substantiate its advertising claims.  But since the National Council Against Health Fraud released several issues pointing out that the claims were based on celebrity endorsement rather than clinical research, the company is more careful about its marketing techniques. 
• Does not contain caffeine or other harmful stimulants
• Ingredients come highly recommended
• May promote fat loss
• Might not work for everyone
• Not enough clinical research
• May cause negative side effects
• Limited availability
Should You Try It?
Met-Rx CLA with Raspberry Ketones may look like a good way to lose weight, but I’m not convinced it’s worth the money.
Clinical research on the ingredients is limited and there isn’t enough evidence to prove CLA with Raspberry Ketone is safe and effective.
Until more information is available, I don’t feel comfortable recommending this product.
 “Conjugated Linoleic Acid.” WebMD. Available from: http://www.webmd.com/vitamins-supplements/ingredientmono-826-CONJUGATED%20LINOLEIC%20ACID.aspx?activeIngredientId=826&activeIngredientName=CONJUGATED%20LINOLEIC%20ACID
 Pilar Parra, Andreu Palou, and Francisca Serra. “Moderate doses of conjugated linoleic acid reduce fat gain, maintain insulin sensitivity without impairing inflammatory adipose tissue status in mice fed a high-fat diet.” Nutr Metab (Lond). 2010; 7: 5. Published online 2010 January 20. doi: 10.1186/1743-7075-7-5. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831902/
 Thom E, Wadstein J, Gudmundsen O. “Conjugated linoleic acid reduces body fat in healthy exercising humans.” J Int Med Res. 2001 Sep-Oct;29(5):392-6. Available from: http://www.ncbi.nlm.nih.gov/pubmed/11725826
 Morimoto C, Satoh Y, Hara M, Inoue S, Tsujita T, Okuda H. “Anti-obese action of raspberry ketone.” Life Sci. 2005 May 27;77(2):194-204. Epub 2005 Feb 25. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15862604
 Oz, Mehmet. “My name for profit? Not anymore.” The Dr. Oz Show. Available from: http://www.doctoroz.com/blog/mehmet-oz-md/my-name-profit-not-anymore
 “Raspbery Ketone.” WebMD. Available from: http://www.webmd.com/vitamins-supplements/ingredientmono-1262-RASPBERRY%20KETONE.aspx?activeIngredientId=1262&activeIngredientName=RASPBERRY%20KETONE
 Muscles, speed & lies: what the … – Google Books. Books.google.com. Retrieved 2011-06-07
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