Clinically Proven Diet Pill Ingredients Review

Clinically Proven Diet Pill Ingredients

More and more companies are using clinically proven ingredients in their weight loss pills. Why? Well, they have been clinically proven to work. As a consumer, you know you are getting a product that has been verified to be not only clinically safe for consumption, but has been scientifically proven to help you lose weight. These ingredients are a bit more pricey, but I am willing to bet that you would pay a few dollars more for a product that is clinically proven.

Here is a list Clinically-Proven diet pill ingredients along with products currently using them in effective dosages:

ForsLean

What is ForsLean?

Forslean is a weight loss supplement that is manufactured by Sabinsa Corporation. Sabinsa Corporation says that it is a patented Phytonutrient for weight management that promotes lean body mass. The main active ingredient in Forslean is the root extract of Coleus Forskohlii. Coleus Forskohlii is an ancient ayurvedic plant that is a member of the mint and lavender family. It grows in the mountains in Asia and is becoming an increasingly popular ingredient in many natural weight loss products.

There is a very detailed website available for Forslean. The website contains a number of scientific papers detailing research carried out on the weight loss properties of Coleus Forskohlii in Japan, the USA and India. These trials do show a modest weight loss benefit that can be linked to the use of Coleus Forskohlii. The active ingredient in Coleus Forskohlii is Forskolin. Forskolin apparently initiates a chemical process in the body that results in a burning of energy and fat cells.

How Does ForsLean Work?

Forskolin increases thyroid activity, which in turn increases the rate of your metabolism and hence results in fat burning.  Forslean was actually Patented for its ability to INCREASE Lean Muscle Tissue which leads to Long Term Fat Loss Success. Coleus forskohlii is an ancient Ayurvedic plant and member of the mint and lavender family, which grows in the mountains of Asia. Recent research has shown that the active ingredient in coleus is forskolin, which plays a major role in a variety of important cellular functions, including inhibiting histamine release, relaxing muscles, increasing thyroid function, and increasing fat-burning activity.

Though scientists are only just confirming the many benefits of coleus, there’s a definite “buzz” circulating about its fat loss capabilities. The main argument for using it to shed unwanted fat is that the active chemical forskolin initiates a cascade of chemical reactions that cause fat cells to release their energy and melt away. Forskolin initiates a similar cascade of chemical reactions as ephedrine without stimulating adrenergic receptors, thus making Forslean a much safer alternative to ephedrine.

A new study using ForsLean, indicates that it could be helpful in helping maintain weight after weight loss.

ForsLean Clinical Study

The 12-week study was conducted at Baylor University’s Center for Exercise, Nutrition & Preventative Health Research. It involved 23 overweight women who were randomized to receive either 250mg of ForsLean (10 percent diterpene forskolin standardization) or a placebo twice a day.

The researchers measured their body composition, body weight, and psychometric instruments were obtained at baseline, four, eight and 12 weeks. Fasting blood samples and dietary records were also obtained at the start and end of the trial. Side effects were recorded each week.

The results, published in the Journal of the International Society of Sports Nutrition (2(2): 54-62, 2005), showed that women who received the ForsLean experienced a decrease in body mass and scanned mass and reported less fatigue and hunger. There were no significant differences in fat mass.

No significant interactions were observed; most notably, despite previous research indicating that Coleaus forskohlii may cause an increase in heart rate and decrease in blood pressure, this was not seen in the current study.

“The results suggest that CF does not appear to promote weight loss but may help mitigate weight gain in overweight females with apparently no clinically significant side effects,” concluded the researchers.

However they said that decreases were seen in carbohydrate, fat and energy intake in both groups over the study period, which may have been due to participants attempting to assist the weight loss process. Differences between the groups may have been observed if a study diet had been prescribed.

The researchers said that Coleaus forskohlii has the potential to influence the loss and management of overall body weight as a means of maintaining weight after weight loss, but that further research into its capabilities is required.

Recommended dosage

• Sabinsa’s preliminary clinical study with ForsLean® showed that a dose that provides 25 mg of forskohlin twice a day could help improve overall body composition by increasing bulk due to lean body mass while decreasing bulk due to body fat.
• Thus, the use of ForsLean® helps to maintain a healthy body composition rather than to induce weight loss.
• In view of this finding, ForsLean® could potentially benefit not only overweight people but also those individuals who are actively involved in athletic training or body building, seeking to attain a higher lean body mass to body fat ratio.
• Sabinsa Corporation strongly recommends the use of a sensible diet along with an exercise regimen of 30-45 minutes duration (at least three days a week) for effective weight management. Natural products such as ForsLean® may enhance such measures and help to achieve the desired results.

Diet Pills Using ForsLean: Apidexin, Anoretix, LipoFuze, Liporexall, Lipovox  Hardcore Detox, PatenTrim, ThermoDrenix, Slim10

Guggule EZ100

Guggulsterones are a mixture of several compounds isolated from the plant Commiphora Mukul (also called Gum Guggul). Carefully planned scientific studies show that guggulsterones reduce bodyweight, mostly due to their stimulating effect on the thyroid gland, which controls your metabolic rate.

Who is it used for?

Guggulsterones are useful for anyone who wants to lose weight, particularly for those who have been trying to lose weight for some time. Unlike supplements such as ephedrine, guggulsterones do not stimulate the nervous system, and are generally considered to be one of the safest supplements available.

How does it work?

Carefully planned scientific studies show that guggulsterones are highly effective at accelerating fat loss, mainly due to their stimulating effect on the thyroid gland. The thyroid hormones are among the most important hormones. They control your metabolic rate, which dictates how many calories you burn each day. When your metabolic rate slows down, which it does when you go on a diet, you automatically burn fewer calories each day. This means that the rate at which you lose weight slows down.

However, guggulsterones naturally stimulate the activity of the thyroid gland, returning your metabolic rate to where it should be. This means that weight loss becomes faster and easier, as your body naturally burns more calories each day.

Guggulsterone Clinical Study

In one study carried in the journal Current Therapeutic Research, test subjects using a supplement containing guggulsterones lost fat three times faster compared to those using diet and exercise alone.

Following the six-week program, the group using the guggulsterone-based supplement lost 9.5 pounds of fat, compared to 3.1 pounds in those who just followed the diet and exercise programme. When the research team measured thyroid activity in three of the subjects, they found an 8-10% increase in thyroid hormone levels.

Guggulsterones are considered to be one of the safest supplements available, and do not stimulate the nervous system in the same way as products like ephedrine. They’re also approved in India for lowering elevated cholesterol and triglyceride levels. Studies show that guggulsterones lower triglycerides and cholesterol as well as LDL and VLDL cholesterol (the “bad” cholesterol). At the same time, it raises levels of HDL cholesterol (the “good” cholesterol).

Diet Pills Using Guggulsterone: Apidexin,  LipoFuze, Thyrovor

Green Tea

Green tea extract often replaces or is used together with caffeine. This combination is being used as a healthier and safer alternative to the popular ephedrine – caffeine – aspirin (ECA) fat burning stack that set the standard for burning fat back when ephedra was legal.

There is more to Green Tea then just burning fat. It also provides additional health benefits. First, Green Tea is a powerful anti-oxidant. Researchers have suggested that the active ingredient (called epigallocatechin gallate, or EGCG) may be up to 200 times more powerful than vitamin E as an oxidant.

Green tea may be useful to slow the spike in blood sugar following a meal. It does this by slowing the action of a particular digestive enzyme called amylase. Amylase is pivotal in the breakdown of starches (carbs), that can cause blood sugar levels to spike following a meal. If you are having trouble managing your glucose levels, you might be interested in Green Tea.

Green tea also helps aid weight loss by increasing your metabolic rate, which causes your body to burn more calories. In a recent study published in the American Journal of Clinical Nutrition (Vol. 81, No. 1, 122-129, January 2005), Green Tea consumption leads to both a lowering of bodyfat and of cholesterol levels.

Diet Pills Using Green Tea: Lipovox  Hardcore Detox, PatenTrim, ThermoDrenix, LipoFuze

Super CitriMax®

Super CitriMax®  is an all-natural, non-stimulant, safe and effective fruit extract from the South Asian fruit Garcinia cambogia, that provides satiety and weight loss benefits.

Super CitriMax® is a patented all-natural, non-stimulant, safe and effective fruit extract used as an ingredient in dietary supplements, functional foods and beverages for satiety (at lower dosages) and weight loss (at higher dosages). Extracted from the South Asian fruit Garcinia cambogia, Super CitriMax® contains standardized levels of (-)hydroxycitric acid (HCA), which has been clinically shown to provide satiety, suppress appetite and inhibit fat production, without stimulating the central nervous system. Clinical research has also shown that higher doses of Super CitriMax® is an all-natural diet aid for reducing or maintaining weight.

Super CitriMax® Clinical Study

In a 90-patient, randomized, double-blind, placebo-controlled human clinical study, researchers at Georgetown University Medical Center and Creighton University School of Pharmacy assessed changes in body weight, lipid profile (triglycerides, LDL, HDL and total cholesterol), serum serotonin levels (a mechanism of appetite control and eating behavior), Body Mass Index (an indicator of healthy body weight), fat metabolites (malondialdehyde, formaldehyde, acetaldehyde and acetone) and appetite control (food consumption). The study demonstrated that Super CitriMax® is a powerful, all-natural diet aid clinically validated to:

• Curb appetite and reduce food intake
• Burn fat
• Reduce body weight and BMI (three-times greater than diet and exercise alone)
• Maintain normal cholesterol levels
• Promote healthy serotonin levels.

Weight Loss Pills Using Super Citrimax: Apidexin, Anoretix, LipoFuze, Liporexall, Lipovox  Hardcore Detox, PatenTrim, ThermoDrenix, Slim10

Tonalin CLA

Tonalin CLA doesn’t contain stimulants, and is designed for safe weight management.

CLA, a polyunsaturated fatty acid, found naturally in ruminant animals like cows, lowers the amount of fat normally stored after meals, helping the body to break down and efficiently use fat. However the changes during the past 30 years in how cattle are raised (grain fed vs. grass fed) coupled with the trend toward low-fat dairy and reduced beef consumption have drastically reduced the amount of CLA humans acquire through diet. It is thought that CLA has two main sites of action: the adipocytes or fat cells, the principal site of fat storage, and the skeletal muscle cells, the principal site where fat is burned for energy. It has been proposed that CLA decreases body fat mass through four actions: by decreasing the amount of fat stored after eating, increasing the rate of fat metabolism, increasing the rate of fat breakdown in fat cells, and decreasing the total number of fat cells.

As the latest research shows, CLA’s primary benefit is body fat reduction and helping to prevent fat regain – and as such it could be a valuable addition to a healthy diet and exercise program for weight management.

Tonalin CLA Clinical Study

A two-year study just published in the April issue of the prestigious Journal of Nutrition 1 concludes that long-term supplementation with conjugated linoleic acid (Tonalin® CLA) is safe and well-tolerated. Furthermore, it confirms that taking CLA decreases BFM and maintains LBM, and so also aids weight management, reducing the potential ‘yo yo’ effect often associated with diet plans.

“This study is particularly exciting because it was intended to confirm the safety of Tonalin® CLA, but it went an important step further demonstrating that the people taking CLA also maintained their lean body mass and didn’t regain the body fat they’d lost,” said Nina Likins, Tonalin® CLA Marketing Manager. “It’s hard enough top lose body fat and even more difficult to keep it off, so this new research will be welcome news to dieters and those that formulate clinically proven products for this population,” she explained.

Overweight subjects who took 3.4 grams of CLA per day lost body fat in the first 12 months of the study, and were able to avoid regaining that fat in the second 12 months. The results of the study corroborate and expand upon earlier findings, published last spring in the American Journal of Clinical Nutrition, which revealed that CLA reduced body fat mass in overweight, but otherwise healthy, adults by as much as 9 percent. They also reveal that people with the highest body mass index (BMI) and body fat mass (BFM), especially women were more likely to lose body fat than those with lower BFM.

Weight management is key, as research has shown that almost all dieters regain the weight they have lost within five years. This study shows that healthy, overweight participants taking a conjugated linoleic acid supplement (Tonalin® CLA) for two years lost body fat and did not regain it. “CLA helped study participants keep off lost weight while maintaining lean body mass – which keeps the metabolism going strong and burning calories, thereby reducing the chances of weight regain,” said Dr. Jean-Michel Gaullier of Scandinavian Clinical Research in Kjeller, Norway, and project manager of the CLA study.

“Having a product that reduces the health risks of going on and off diets – the ‘yo-yo’ effect – is groundbreaking. Interest in CLA has been spurred by consumers’ increased demand for safe, stimulant-free products for reducing unwanted inches,” said Dr. Michael W. Pariza, director of the Food Research Institute (University of Wisconsin-Madison) and a renowned CLA expert.

Another important finding is that CLA supplementation helps lower levels of leptin. High levels of the hormone leptin are associated with increased body weight. Over the course of 24 months, leptin levels dropped 20-35 percent as study subjects lost body fat.

This is the first study to document the long-term safety and efficacy of CLA supplementation over a two-year period without lifestyle or dietary restrictions. It began as a randomized, double-blind, placebo-controlled study over a 12-month period, but was later extended by a further 12 months as open treatment. Of the 157 subjects that completed the original study, 134 volunteered to participate in the extension, and 125 completed the entire 24-month study. The second 12 months were aimed at evaluating the safety of CLA and assessing its effects on body composition (body fat mass, lean body mass, bone mineral mass, body weight and BMI) over a prolonged period of time.

Overall, CLA supplementation for 24 months in healthy, overweight adults was well tolerated. Most of the adverse effects reported during the double-blind phase were unrelated to the use of CLA (94 percent). The remainder (6 percent) were rated “mild” reactions, with the most frequent complaints being gastrointestinal in nature, evenly distributed over all groups including the placebo group.

Weight Loss Pills Using Tonalin CLA: Anoretix,  Liporexall, Lipovox  Hardcore Detox,  Slim10

Advantra-Z

Advantra-Z is an extract of a citrus fruit (C. aurantium) containing a family of indirect-acting adrenergic amines (B-sympathicomimetics) that facilitate utilization of energy substrates, stimulate metabolic processes, favor uptake of amino acids into muscle, increase lipolysis (breakdown of fat) and can exert mild hunger-suppressant effects.

Advantra Z^® is the only patented thermogenic ingredient for weight loss and physical performance on the market today.

How Much Advantra-Z Should You Take?

Advantra Z^® is available in four effective potencies based on standardized amounts of synephrine (5%, 6%, 10% and 30%).  Nutratech suggests a daily range between 100 and 120 mgs of synephrine divided over 2-3 servings per day depending on the end user and the inclusion of other ingredients in the finished formula like stimulants and caffeine.

If the customer’s target user is a bodybuilder, the dosage should be on the high-end of that daily range.  If the customer’s target user is just a general consumer, the dosage should be on the low-end of that daily range.

It is also important that the formulator of a finished diet or sports nutrition product consider the total formula and the synergistic application of Advantra Z^® with those other ingredients to determine quantity and potency of Advantra Z^® in that finished product.

Advantra-Z Clinical Study

A new scientific study led by a staunch critic of performance-enhancing dietary supplements has found that exercise tolerance improved – and no significant adverse events occurred – following use of a performance-enhancing dietary supplement containing Advantra Z®, a patented Citrus aurantium (bitter orange) extract for weight-management and sports nutrition distributed exclusively by Nutratech, Inc.

The three-arm, double-blind, placebo-controlled, crossover study, “Human Pharmacology of a Performance-Enhancing Dietary Supplement Under Resting and Exercise Conditions,” was published online in the British Journal of Clinical Pharmacology on March 13, 2008. It was conducted by Christine A. Haller, M.D. – of the University of California, San Francisco – who has been a frequent and outspoken critic of performance-enhancing dietary supplement usage. However, this is the second study from Haller to demonstrate positive results for dietary supplements containing Advantra Z.

“This study is a ringing endorsement of sports nutrition supplements, as well as Advantra Z,” said Bob Green, Nutratech president. “The researchers found that exercising was easier 83 percent of the time when people used a leading sports nutrition supplement.”

Green noted that the study also corroborates the results of numerous safety evaluations conducted on Advantra Z since 1997 – notably analysis by independent Laboratory Chromadex, which proved Advantra Z contains the stable p-isomer of synephrine, not the m-isomer that is believed to potentially increase blood pressure in some users.

Haller found that test subjects reported exercise was less difficult after using Twinlab’s Ripped Fuel Extreme Cut®, which incorporated Advantra Z as the source for Citrus aurantium.

“Perceived exertion during exercise showed that supplement use ameliorated the increase in exertional effort reported over time with placebo …. Dietary supplement sessions were rated easier than placebo sessions 83 percent of the time.”

In addition, after the initial post-dosing increases in blood pressure, there were no increases in post exercise heart rate, systolic blood pressure, or temperature – and no differences in exercise related oxygen consumption, serum lactate, or insulin.

Haller measured plasma synephrine (the dominant amine in Citrus aurantium) and caffeine concentrations over twelve hours, and monitored vital signs, serum electrolytes, oxygen consumption, and perceived exercise exertion in ten healthy adults between the ages of 20 and 31. Subjects ingested one dose of the supplement under resting conditions and one hour prior to 30 minutes of moderate exercise on a stationary bicycle.

Haller also found that diastolic (resting) blood pressure and postprandial (after eating a meal) plasma glucose increased after exercise with supplement use and stated that dietary supplement use could be detrimental in some people.

“That conclusion seems dubious. It’s definitely an overstatement because the study doesn’t account for a number of third variables. For example, how individual metabolisms and fitness levels react differently to food and exercise,” said Green. “Most importantly, it’s common knowledge that blood pressure goes up during and after exercise, and increases in glucose are normal after eating.”

However, Green added that Nutratech has always strongly advised manufacturers to properly label their products and urge consumers – particularly those with hypertension, heart disease or other pre-existing conditions – to consult with health care providers before embarking on any dietary supplement regimen.

This is the second study from Haller to cite findings supporting Advantra Z. In “Hemodynamic Effects of Ephedra-Free Weight-Loss Supplements in Humans,” published September 9, 2005 in The American Journal of Medicine, Haller studied Xenadrine EFX, a weight-management supplement containing Advantra Z. The study found: Even in eight-fold higher dosages (40 mg synephrine per dose), Citrus aurantium (Advantra Z) did not affect blood pressure. In fact, blood pressure went down  slightly.

Diet Pills Using Advantra-Z: Anoretix,   Lipovox  Hardcore Detox,  Slim10, Nuphedrine, MiracleBurn

NeOpuntia

NeOpuntia® is a unique lipophilic fiber, made from dehydrated Opuntia ficus-indica cactus leaves. It is a 100% natural, functional ingredient which can be incorporated into dietary supplements for weight management and well-being applications. NeOpuntia® has the amazing ability to attract and bind to fats when in their presence.

NeOpuntia Clinical Studies

A comprehensive set of studies was conducted on NeOpuntia® in order to confirm its lipophilic properties. The latest clinical study goes even further : it also reveals  its health benefits related to blood lipid levels regulation.

In vitro tests showed that the soluble and insoluble fibers contained in NeOpuntia® physically interacts with fats :

• Step 1 : Hydrophobic interaction takes place between fats & insoluble fibers
• Step 2 : Primary interactions are stabilized thanks to the soluble fibers (polysaccharides which create a fluid gel, stable at any pH).

NeOpuntia® has been proven to  reduce fat absorption into the body, with instant effect starting in the stomach.

In vitro tests simulating gastro-intestinal conditions showed that :

• NeOpuntia® could decrease fatty acid bioavailability by more than 28%.
• NeOpuntia® lipophilic capacity is much higher than the one of Chitosan

A pilot clinical study also suggests that 1.6 g of NeOpuntia® per meal increases fat excretion on an average of 27%, compared to placebo.

Diet Pills Using NeOpuntia: Apidexin, Anoretix,  Liporexall, Lipovox  Hardcore Detox, Slim10

Phase 2®

Phase 2® Carb Controller is an all-natural, non-stimulant white bean extract that is used as an ingredient in a variety of nutritional supplements. It is the first carbohydrate blocker clinically proven in multiple studies to delay the digestion and absorption of carbohydrates. This, in turn, reduces the caloric impact of starchy foods, and also lowers the glycemic index. When used in conjunction with a sensible diet and exercise, Phase 2 may assist in weight control. While there is no such thing as a magic weight control pill, Phase 2 may enable people concerned with weight control and/or blood glucose levels to enjoy carb-rich foods again in moderation.

Phase-2 Clinical Studies

Phase 2 has been the subject of multiple clinical studies that have proven its safety and effectiveness. In 2006, the US Food & Drug Administration conducted an extensive review of clinical data and information on Phase 2, and announced that it does not object to weight control and starch reduction claims for Phase 2, and supplements containing it.

Diet Pills Using Phase2: Apidexin, Anoretix, LipoFuze, Liporexall, Lipovox  Hardcore Detox, Slim10

Orlistat

Orlistat is a drug that promotes loss of weight by preventing the digestion and absorption of fat in food. In the intestine, an enzyme called lipase (produced primarily by the pancreas) breaks apart fat in food so that it can be absorbed into the body. Orlistat blocks the action of lipase and thereby prevents the breakup and absorption of fat. Orlistat blocks absorption of about 25% of the fat in a meal. The unabsorbed fat is excreted in the stool. The FDA approved Orlistat by prescription in 1999. Alli, a lower dose formulation of Orlistat, was approved for purchase without a prescription “over the counter” in 2007.

The recommended prescription dose for Xenical is one capsule (120 mg) three times daily. The recommended dose for Alli is 60 mg three times daily. Orlistat should be taken one hour after or during a meal containing about 15 mg of fat. Meals without fat do not require Orlistat. No additional benefit has been shown when Orlistat was taken in doses greater than 120 mg. Patients should eat a nutritionally balanced, reduced calorie diet that contains approximately 30% of calories from fat. Alli includes an individually tailored online weight loss support program.

Some dietary vitamins bind to fat (vitamins A, D, E and beta- carotene). When Orlistat is taken, these vitamins are not absorbed and are eliminated in the stool in increased amounts along with the fat. Therefore, patients taking Orlistat should take a multivitamin containing these “fat-soluble” vitamins to ensure that adequate amounts of the vitamins are available for absorption. To ensure that the vitamins in the multivitamins are not bound to fat like the vitamins in the diet, the multivitamin should be taken at least two hours before or several hours after the Orlistat.

Orlistat Side Effects

The most common side effects of orlistat are oily spotting on underwear, flatulence, urgent bowel movements, fatty or oily stools, increased number of bowel movements, abdominal pain or discomfort, and inability to control stool (incontinence).

Between 1 in 250 and 1 in 70 patients experienced one or more of these symptoms in the first year. Generally, the side effects occurred within three months of starting therapy. In about 50% of patients, the side effects resolved within one to four weeks, but the effects in some patients lasted six months or longer.

To reduce the occurrence of these side effects, meals should contain no more than 30% fat because it is the unabsorbed fat that causes most of the symptoms. alli causes fewer side effects because it contains half the dose of prescription-strength orlistat. Patients receiving orlistat with a history of oxalate kidney stones may develop increased levels of oxalate in their urine, which may increase the risk of kidney stones.

Update: Orlistat has been recently linked to liver failure. “WEIGHT loss pill Xenical is under a safety cloud, with US reports linking it to liver failure. The US Food and Drug Administration this week notified doctors and patients it has begun a review of the drug. The review is in response to 32 reports in the past decade of serious liver injury, including six cases of liver failure, in patients using the drug orlistat, which is marketed as Xenical or Alli. The reports included symptoms such as jaundice, weakness and abdominal pain.”

Diet Pills Using Orlistat: Alli

7Keto DHEA

7-Keto produces fat loss through the process of thermogenesis. This term refers to the creation of heat, which is one of the forms of energy produced when the body’s cells metabolize the food we eat. Greater amounts of thermogenesis boost the body’s metabolic rate which increases the conversion of stored fat into energy.

7-Keto enhances the activity of three thermogenic enzymes that stimulate fatty acid oxidation in the liver. These thermogenic-en-hancing enzymes are fatty acyl CoA oxidase, malic enzyme, and glycerol-3-phosphate dehydrogenase. These enzymes drive the liver cells to burn fatty acids for energy, which causes a lowering of triglycerides in the liver.

Supplementation with 7-Keto has a dramatic effect on boosting levels of these thermogenic-enhancing enzymes. Studies found that fatty acyl CoA oxidase increased by 128%, while malic enzyme jumped 860%. The concentration of glycerol-3-phosphate dehydrogenase increased by 138% as well.

7-Keto Clinical Study

A study published in Current Therapeutic Research revealed just how effective 7-Keto is in inducing fat loss.13 In this randomized, double-blind, placebo-controlled study, 30 overweight adults (28 women and 2 men) were divided into two groups. Group 1 received 100 mg of 7-Keto twice daily for eight weeks, while group 2 took a matching pla-cebo capsule. All subjects participated in an exercise program three times a week that consisted of 50 minutes of aerobic and non-aerobic cross training under the supervision of an exercise physiologist. In addition, each subject was instructed by a registered dietitian to follow an 1800-calorie-a-day diet. The subjects underwent testing for blood chemistry, body composition, blood pressure, and dietary analysis at baseline and at weeks four and eight.

The researchers found that the 7-Keto group lost a significant amount of body weight compared to the placebo group-6.3 versus 2.1 pounds. The 7-Keto group also lost a greater percentage of body fat compared to the placebo group-1.8% versus 0.57%.13 Compared to the placebo group, the 7-Keto group saw a significant increase in thyroid hormone activity that targets fat- burning genes in the mitochondria and adipose tissue.14 No adverse effects were reported.

The results show that 7-Keto can significantly and safely reduce body weight and body fat when combined with exercise and a reduced-calorie diet. This is due to the greatly increased levels of fat-burning enzymes in the liver as well as the elevation of thyroid hormone. These beneficial changes are known to boost basal metabolic rate, making it easier to shed excess pounds.

Supplementation with 7-Keto can therefore help reverse the decline in metabolic rate that makes it so easy to put on weight as we age. Unlike caffeine and ephedrine, 7-Keto does not have a central nervous system stimulating effect caused by nor-adrenalin release, nor does 7-Keto increase heart rate or blood pressure.

Other Benefits of 7-Keto

• Cholesterol Reduction
• Boost Memory
• Improvement in Body Composition

Diet Pills Using 7-Keto: Anoretix,  Liporexall, Lipovox  Hardcore Detox,  Slim10

ChromeMate

ChromeMate is a unique, patented form of biologically active niacin-bound chromium called chromium nicotinate or polynicotinate that dramatically increases the safety and effectiveness of chromium, an essential trace mineral required for normal insulin function.

Chromium helps insulin metabolize fat, turn protein into muscle and convert sugar into energy. Chromium-activated insulin increases the amount of blood sugar available for energy production nearly twenty-fold. ChromeMate® is a unique, patented form of biologically active niacin-bound chromium called chromium nicotinate or polynicotinate that dramatically increases the effectiveness of chromium. Researchers have shown that ChromeMate’s unique, patented oxygen-coordinated niacin-bound chromium complex is the safest and most potent form of chromium available as a dietary supplement.

ChromeMate Clinical Studies

InterHealth Nutraceuticals’ ChromeMate® was found to reduce blood pressure through its effects on the renin-angiotensin system (RAS), a hormone system that regulates long-term blood pressure. A team of researchers, led by Dr. Nicholas Perricone, found that ChromeMate® lowered sugar-induced blood pressure, at least in part, by decreasing the activity of the RAS system.

The study, recently published in the Journal of Inorganic Biochemistry, first confirmed that disturbances in the RAS were significant factors in the elevation of sugar-induced blood pressure, as measured by increased levels of the hormone angiotensin-2. Animals that ingested ChromeMate® experienced a significant decrease in angiotensin-2 levels and blood pressure, thus demonstrating one way that ChromeMate® works to promote healthy blood pressure levels. The study is available through PubMed (PMID: 18374418).

“This research provides important insight into how ChromeMate® works to reduce blood pressure, a significant indicator of cardiovascular health,” stated InterHealth CEO Paul Dijkstra. “These findings are particularly important to those with diabetes since cardiovascular disease is so closely associated with diabetes. ChromeMate® has also been shown to be highly effective in helping to maintain healthy blood sugar levels and body weight, so it represents a triple benefit in the fight against diabetes.”

The study was conducted at Michigan State University College of Human Medicine (East Lansing, MI) by Nicholas Perricone, MD, FACN, Harry Preuss, MD, MACN, CNS, Debasis Bagchi, Ph.D., and Bobby Echard, M.T. Dr. Perricone is a recipient of the Eli Whitney Award for his significant contributions to science, invention and technology. Dr. Preuss, a professor of medicine and pathology at Georgetown University Medical Center (Washington, DC), is known for his significant body of research related to weight loss and insulin control. Dr. Preuss is also author of the best-selling book, The Natural Fat-Loss Pharmacy, and respected researcher and known authority in the field of anti-aging research.

ChromeMate® also reduces cholesterol levels and total cholesterol:HDL (“good”) cholesterol ratios. Animal research suggests that ChromeMate® alleviates injury to the heart muscle, lowers blood pressure, decreases lipid peroxidation and oxidative and DNA damage.

Diet Pills Using ChromeMate: Anoretix,  Liporexall, Lipovox  Hardcore Detox, Slim10, SlendeSlim

Slendesta

Slendesta is a natural potato extract derived from white potatoes, which is one of the most commonly consumed foods. In addition to historical consumption, animal toxicity data and human clinical studies have reported no adverse effects associated with the use of Slendesta Potato Extract when taken as directed.

Slendesta is a patented, safe and natural satiety ingredient for weight management food and food supplements. Slendesta Potato Extract is standardized to its active component, PI2. PI2 promotes the release of CCK, the natural signaling peptide within our body. Once released, CCK travels through the blood targeting various organs, where it induces feelings of fullness and satisfaction known as satiety.

PI2 Clinical Studies on Safety and Efficacy

Clinical studies have collectively demonstrated PI2’s benefits, including that it is a safe and effective natural ingredient that promotes satiety and healthy weight loss. When taken as directed, Slendesta has resulted in statistically significant weight loss and reductions in waist and hip measurements.

Diet Pills Using Slendesta: SlendeSlim

Slimaluma

SLIMALUMA^TM is a proprietary standardized extract of Caralluma Fimbriata, an edible plant used for centuries in India as a famine food and appetite suppressant. SLIMALUMA^TM is a clinically proven, safe and non-toxic dietary supplement that can be used for the management of obesity, by appetite suppression leading to clinically significant weight loss.

Slimaluma Clinical Studies

Two independent clinical trials were done on SLIMALUMA^TM .

1. Clinical Trial at Division of Nutrition, St John’s National Academy of Health Sciences, India.

Results from this clinical trial were subjected to rigorous statistical analysis, using statistical tests are the international norms and approved for double-blind clinical trials. The summary of analysis is presented below.

Slimaluma was clinically proven to decrease body weight, body mass index, waist circumference, hip circumference, body fat, blood pressure and hunger levels.

2. Clinical Trial at Western Geriatric Research Institute, LA, USA.

Subjects were taken from two active practices in the Los Angeles area. The subjects were randomly assigned to either the active group or a placebo group. The trial was carried out on 26 patients, 9 of whom were males. They ranged in age from 31 through 73. One patient nom each category did not show up for the final visit (dropouts).

Out of 18 patients, 15 patients (83.33%) lost weight. Eleven patients (61.11%) lost about six pounds. The highest loss was nine pounds. It is significant that patients with a higher BMI lost more weight. Thirteen out of 18 patients (72.22%) reduced their waist by 0.5 inches to 3 inches. Five out of 18 patients (27.77%) felt an increase in energy while on the active substance. Three out of six placebo patients (50%) gained one pound and one placebo patients lost one pound.

In both the clinical trials done on SLIMALUMA^TM clearly demonstrated that there was reduction in hunger levels, reduction in weight circumference, reduction in fat and reduction in body weight in the active group of participants.

Diet Pills Using Slimaluma: SlendeSlim, Slim10, Nuphedrine

Chromax

Chromax is a patented form of chromium, a trace mineral, is essential to the body’s production of insulin. Insulin is a hormone that stabilizes the body’s blood sugar level.

Research indicates that the majority of people in the United States are chromium deficient. Most people could use chromium in their diets. As chromium levels decrease with age and deficiencies occur with people who do not eat a good balanced diet, chromium supplementation can be very beneficial. Because processed foods have much of the chromium removed, increasing ones chromium content is recommended to sustain proper glucose levels and gain energy. Anyone who likes to live with energy, burn fat, and increase strength and muscle mass would also do well to supplement with chromium.

Chromax Clinical Study

A recent study on this patented form of chromium discovered that the users of Chromax® ate 365 LESS calories per day. It resulted in a 24% reduction in hunger and a 25% reduction in food intake.

Diet Pills Using Chromax: SlendeSlim

Glucomannan

Glucomannan is a dietary fiber that helps to increase stool bulk by absorbing water. This helps stool pass more easily through the colon, preventing unnecessary stress to the colon.

Because it is a fiber, glucomannan can assist with weight loss and healthy weight maintenance by expanding in the stomach and absorbing fats. Absorbed fats are eliminated from the body and do not undergo digestion, thus nullifying their caloric effect. Also, glucomannan occupies space in the stomach and provides feelings of fullness. You’ll eat less when this happens, and this will direct your body to tap into body fat stores for energy. Simply, you’ll have a better chance of burning fat and losing weight when you use glucomannan.

Glucomannan is a popular ingredient in nutritional weight-loss supplements because of its weight loss and insulin controlling abilities.

Glucomannan Clinical Study

Research has indicated that patients treated with oral glucomannan have decreased body weight compared with control groups. In one study involving an 8-week cardiac rehabilitation program, patients were given 1.5 grams of glucomannan twice daily. Body weight among treated patients decreased by 3.3 pounds at the end of 4 weeks and by 4.85 pounds at the end of 8 weeks. These losses were significant when compared with the placebo group.

Diet Pills Using Glucomannan: Phenomannan, Dieters Cheating Caps, MiracleBurn, Clinicallix

5-HTP

5-Hydroxytryptophan (5-HTP) is an amino acid that is the intermediate step between tryptophan and the important brain chemical serotonin. There is a massive amount of evidence that suggests that low serotonin levels are a common consequence of modern living. The lifestyle and dietary practices of many people living in this stress-filled era results in lowered levels of serotonin within the brain. As a result, many people are overweight, crave sugar and other carbohydrates, experience bouts of depression, get frequent headaches, and have vague muscle aches and pain.

5-HTP Clinical Study

In a clinical study, 19 obese women were tested in a double-blind, crossover study by researchers at the University of Rome to evaluate the effects of 5-HTP on food intake, mood, and weight loss.

During two five-week periods 15 of the 19 women reported loss of appetite; however, only six women taking the placebo made this claim. Prior to treatment, the average daily intake of food was 2,900 calories. Women taking the placebo dropped to 2,300 calories — researchers indicate that merely being monitored on a weight-loss program motivates people to eat less. However, the big drop was seen among the 5-HTP takers — 1,100 to 1,800 calories, averaging a weight loss of five pounds.

Diet Pills Using 5-HTP: Ephedrasil Hardcore, Leptorexin

Yerba mate, Guarana, and Damiana

For centuries Yerba Mate, Guarana and Damiana have been used by tribes to help stimulate their energy levels and prolong feelings of fullness.

Yerba mate, Guarana, and Damiana  Clinical Study

In a placebo controlled, double blind trial in Charlottenlund Medical Center in Denmark, 44 overweight subjects were split into two groups and examined. One group was administered a compound containing Yerbe Mate, Guarana, and Damiana and the other group was administered a placebo. Both groups were observed before and after being administered their compounds after 45 days. The group administered the Guarana, Yerba Mate, and Damiana showed significant weight loss.

In fact, those taking the herbal combination lost an average of 11.2 pounds after 45 days while those that were on the placebo lost 0.7 pounds.

Diet Pills Using Yerba Mate, Guarana and Damiana: Clinicallix

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